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  • 兔抗ROCK1多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW20523
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱兔抗ROCK1多克隆抗體 

英文名稱 Anti-ROCK1 rabbit polyclonal antibody

抗      原 ROCK1

別      名: ROCK-I; P160ROCK
 
儲(chǔ)      存 冷凍(-20℃)

宿      主 Rabbit

相關(guān)類別: 一抗

反應(yīng)種屬: Human, Mouse, Rat

標(biāo)記物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity.

Applications:

ELISA, IHC

Name of antibody:

ROCK1

Immunogen:

Fusion protein of human ROCK1

Full name:

Rho-associated, coiled-coil containing protein kinase 1

Synonyms:

ROCK-I; P160ROCK

SwissProt:

Q13464

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and human gastric cancer

IHC Recommend dilution:

25-100