兔抗RIN1多克隆抗體

Background:

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Applications:

WB

Name of antibody:

RIN1

Immunogen:

Synthesized peptide derived from internal of human RIN1.

Full name:

Ras and Rab interactor 1

Synonyms：

0

SwissProt:

Q13671

WB Predicted band size:

84 kDa

WB Positive control:

K562 cells lysate

WB Recommended dilution:

500-3000