Background: |
This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
Applications: |
ELISA, IHC |
Name of antibody: |
FAN1 |
Immunogen: |
Synthetic peptide of human FAN1 |
Full name: |
FANCD2 and FANCI associated nuclease 1 |
Synonyms: |
KMIN; hFAN1; MTMR15; KIAA1018 |
SwissProt: |
Q9Y2M0 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human lung cancer and Human ovarian cancer |
IHC Recommend dilution: |
30-150 |
