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  • TIRAP抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW20019
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：60
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中文名稱： TIRAP抗原（重組蛋白）

英文名稱： TIRAP Antigen (Recombinant Protein)

別     名：  Mal; wyatt; BACTS1; MyD88-2

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

toll-interleukin 1 receptor (TIR) domain containing adaptor protein

Synonyms:

Mal; wyatt; BACTS1; MyD88-2

Swissprot:

P58753

Gene Accession:

BC032474

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.