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中文名稱：兔抗PTPN11多克隆抗體
英文名稱： Anti-PTPN11 rabbit polyclonal antibody
別 名： CFC, NS1, SHP2, BPTP3, PTP2C, PTP-1D, SH-PTP2, SH-PTP3
抗 原： PTPN11
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
相關(guān)類別： 一抗
反應(yīng)種屬： Human, Mouse, Rat
標(biāo)記物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, WB |
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Name of antibody: |
PTPN11 |
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Immunogen: |
Fusion protein of human PTPN11 |
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Full name: |
protein tyrosine phosphatase, non-receptor type 11 |
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Synonyms： |
CFC, NS1, SHP2, BPTP3, PTP2C, PTP-1D, SH-PTP2, SH-PTP3 |
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SwissProt: |
Q06124 |
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ELISA Recommended dilution: |
1000-5000 |
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WB Predicted band size: |
68 kDa |
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WB Positive control: |
NIH/3T3 cells |
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WB Recommended dilution: |
200-1000 |
