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    • 品牌 : 通蔚生物
    • 目錄號 : TW19280
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
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中文名稱: MR1 抗原(重組蛋白)

英文名稱: MR1 Antigen (Recombinant Protein)

別     名:  major histocompatibility complex, class I-related; HLALS

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 110-257 amino acids of human MR1

技術(shù)規(guī)格

Full name:

major histocompatibility complex, class I-related

Synonyms:

HLALS

Swissprot:

Q95460

Gene Accession:

BC012485

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.