兔抗EIF4E2多克隆抗體

Background:

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:9582349, PubMed:17368478, PubMed:25624349). Acts as a repressor of translation initiation (PubMed:22751931). In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (By similarity).

Applications:

ELISA, IHC

Name of antibody:

EIF4E2

Immunogen:

Fusion protein of human EIF4E2

Full name:

eukaryotic translation initiation factor 4E family member 2

Synonyms:

4EHP; IF4e; 4E-LP; h4EHP; EIF4EL3

SwissProt:

O60573

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200