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021-54845833/15800441009
中文名稱： 兔抗MORF4L2多克隆抗體
英文名稱： Anti-MORF4L2 rabbit polyclonal antibody
別 名： mortality factor 4 like 2; MRGX; MORFL2
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MORF4L2
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型：rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The members of the mortality factor family include mortality factor 4 (MORF4), mortality factor 4 like 1 (MORF4L1), also known as MORF4-related gene 15 (MRG15), and mortality factor 4 like 2 (MORF4L2), also known as MORF-4 related gene X (MRGX). The human MORF4 gene maps to chromosome 4q34.1. MORF4 induces a senescent-like phenotype in complementation group B immortal cell lines. The genes encoding MORF4L1 and MORF4L2 map to chromosomes 15q25.1 and Xq22.2, respectively. MORF4, MORF4L1 and MORF4L2 each contain a C-terminal leucine zipper. An association between MORF4L1, Rb (retinoblastoma tumor suppressor) and PAM14 (protein associated with MORF4L1) suggests a role for MORF4L1 in transcription regulation. MORF4L1 also associates with the histone acetyl transferase MOF. In addition, MORF4, MORF4L1 and MORF4L2 interact with mSin3A and TLE (transducin-like enhancer of split). The MORF/mSin3A/TLE association may repress transcription. In Purkinje cells, MORF4L1 localizes to the dendrites and the nuclei. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MORF4L2 |
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Immunogen: |
Synthetic peptide of human MORF4L2 |
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Full name: |
mortality factor 4 like 2 |
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Synonyms: |
MRGX; MORFL2 |
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SwissProt: |
Q15014 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human gastric cancer |
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IHC Recommend dilution: |
25-100 |
