中文名稱: 兔抗MLLT11多克隆抗體
英文名稱: Anti-MLLT11 rabbit polyclonal antibody
別 名: AF1Q
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: MLLT11
反應(yīng)種屬: Human, Mouse, Rat
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. |
Applications: |
ELISA, IHC |
Name of antibody: |
MLLT11 |
Immunogen: |
Full length fusion protein |
Full name: |
MLLT11 transcription factor 7 cofactor |
Synonyms: |
AF1Q |
SwissProt: |
Q13015 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human brain |
IHC Recommend dilution: |
25-100 |