中文名稱:FARP2抗原(重組蛋白)
英文名稱: FARP2 Antigen (Recombinant Protein)
別 名: FIR; FRG; PLEKHC3
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 1-200 amino acids of human FARP2 |
Full name: |
FERM, ARH/RhoGEF and pleckstrin domain protein 2 |
Synonyms: |
FIR; FRG; PLEKHC3 |
Swissprot: |
O94887 |
Gene Accession: |
BC021301 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity). |