中文名稱:EIF2B3 抗原(重組蛋白)
英文名稱: EIF2B3 Antigen (Recombinant Protein)
別 名: eukaryotic translation initiation factor 2B subunit gamma; EIF-2B; EIF2Bgamma
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 202-401 amino acids of human EIF2B3 |
Full name: |
eukaryotic translation initiation factor 2B subunit gamma |
Synonyms: |
EIF-2B; EIF2Bgamma |
Swissprot: |
Q9NR50 |
Gene Accession: |
BC018728 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |