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  • ATP6V0A1 抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW18542
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：90
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中文名稱：ATP6V0A1 抗原（重組蛋白）

英文名稱： ATP6V0A1 Antigen (Recombinant Protein)

別      名： ATPase H+ transporting V0 subunit a1; a1; Stv1; VPP1; Vph1; ATP6N1; ATP6N1A

儲      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概      述：

Fusion protein corresponding to a region derived from 1-200 amino acids of human ATP6V0A1


技術(shù)規(guī)格：

Full name:

ATPase H+ transporting V0 subunit a1

Synonyms:

a1; Stv1; VPP1; Vph1; ATP6N1; ATP6N1A

Swissprot:

Q93050

Gene Accession:

BC032398

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene.