ZFYVE27抗原（重組蛋白）

Full name:

zinc finger FYVE-type containing 27

Synonyms:

SPG33; PROTRUDIN

Swissprot:

Q5T4F4

Gene Accession:

BC030621

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.