中文名稱:TRMT12抗原(重組蛋白)
英文名稱: TRMT12 Antigen (Recombinant Protein)
別 名: TYW2; TRM12
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 249-448 amino acids of human TRMT12 |
Full name: |
tRNA methyltransferase 12 homolog |
Synonyms: |
TYW2; TRM12 |
Swissprot: |
Q53H54 |
Gene Accession: |
BC011713 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006). |