中文名稱:PPP2R1A抗原(重組蛋白)
英文名稱: PPP2R1A Antigen (Recombinant Protein)
別 名: MRD36; PP2AA; PR65A; PP2AAALPHA; PP2A-Aalpha
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 390-589 amino acids of human PPP2R1A |
Full name: |
protein phosphatase 2 scaffold subunit Aalpha |
Synonyms: |
MRD36; PP2AA; PR65A; PP2AAALPHA; PP2A-Aalpha |
Swissprot: |
P30153 |
Gene Accession: |
BC001537 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. |