中文名稱(chēng): ITGB2 抗原(重組蛋白)
英文名稱(chēng): ITGB2 Antigen (Recombinant Protein)
別 名: integrin, beta 2 (complement component 3 receptor 3
and 4 subunit); LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概述
Fusion protein corresponding to a region derived from 124-363 amino acids of human ITGB2 |
Full name: |
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
Synonyms: |
LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1 |
Swissprot: |
P05107 |
Gene Accession: |
BC005861 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. |