中文名稱(chēng): ITGA5 抗原(重組蛋白)
英文名稱(chēng): ITGA5 Antigen (Recombinant Protein)
別 名: integrin, alpha 5 (fibronectin receptor, alpha polypeptide); FNRA; CD49e; VLA-5; VLA5A
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概述
Fusion protein corresponding to a region derived from 850-1049 amino acids of human ITGA5 |
Full name: |
integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
Synonyms: |
FNRA; CD49e; VLA-5; VLA5A |
Swissprot: |
P08648 |
Gene Accession: |
BC008786 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes. |