中文名稱:IRAK3抗原(重組蛋白)
英文名稱: IRAK3 Antigen (Recombinant Protein)
別 名: ASRT5; IRAKM
概述
Fusion protein corresponding to a region derived from 165-452 amino acids of human IRAK3 |
Full name: |
interleukin-1 receptor-associated kinase 3 |
Synonyms: |
ASRT5; IRAKM |
Swissprot: |
Q9Y616 |
Gene Accession: |
BC057800 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. |