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      PDCD1抗原 
      
                
      
                  
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	中文名稱： PDCD1抗原 

    

    
	
    
    

    

    
	英文名稱： PDCD1 Antigen

    

    
	
    
    

    

    
	相關(guān)類別： 抗原 
    

    
    

    

    
	儲(chǔ)    存： 冷凍（-20℃） 
    

    
    

    

    
	概述

    

    
	
    
    

    

    
	Synthetic peptide corresponding to a region derived from 270-284 amino acids of human Programmed cell death 1

    

    
	
    
    

    

    
	技術(shù)規(guī)格
	
    
		
			
    
				
					
    
						Full name
					
    
				    		
				
					
    
						Programmed cell death 1
					
    
				    		
			
    
			
    
				
					
    
						Synonyms
					
    
				    		
				
					
    
						PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l
					
    
				    		
			
    
			
    
				
					
    
						Swissprot
					
    
				    		
				
					
    
						Q15116
					
    
				    		
			
    
			
    
				
					
    
						Gene Accession
					
    
				    		
				
					
    
						NP_005009
					
    
				    		
			
    
			
    
				
					
    
						Background
					
    
				    		
				
					
    
						This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.