中文名稱(chēng):VPS18 抗原(重組蛋白)
英文名稱(chēng): VPS18 Antigen (Recombinant Protein)
別 名: VPS18, CORVET/HOPS core subunit; PEP3
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概 述:
Fusion protein corresponding to a region derived from 332-581 amino acids of human VPS18 |
Full name: |
VPS18, CORVET/HOPS core subunit |
Synonyms: |
PEP3 |
Swissprot: |
Q9P253 |
Gene Accession: |
BC001513 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. |