中文名稱:SUFU 抗原(重組蛋白)
英文名稱: SUFU Antigen (Recombinant Protein)
別 名: SUFU negative regulator of hedgehog signaling; SUFUH; JBTS32; SUFUXL; PRO1280
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概述:
Fusion protein corresponding to C terminal 250 amino acids of human SUFU |
Full name: |
SUFU negative regulator of hedgehog signaling |
Synonyms: |
SUFUH; JBTS32; SUFUXL; PRO1280 |
Swissprot: |
Q9UMX1 |
Gene Accession: |
BC013291 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants. |