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  • IKZF3抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17450
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:90
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中文名稱:IKZF3抗原(重組蛋白)

英文名稱: IKZF3 Antigen (Recombinant Protein)

別      名: AIO; AIOLOS; ZNFN1A3

儲      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to C terminal 250 amino acids of human IKZF3


技術(shù)規(guī)格:

Full name:

IKAROS family zinc finger 3 (Aiolos)

Synonyms:

AIO; AIOLOS; ZNFN1A3

Swissprot:

Q9UKT9

Gene Accession:

BC032707

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.