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  • FGFR1OP抗原(重組蛋白)

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    價(jià)格:
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17292
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱:  FGFR1OP抗原(重組蛋白)

英文名稱: FGFR1OP Antigen (Recombinant Protein)

別      名 FOP

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別 抗原

概  述:

Fusion protein corresponding to N terminal 249 amino acids of human FGFR1OP


技術(shù)規(guī)格:

Full name:

FGFR1 oncogene partner

Synonyms:

FOP

Swissprot:

O95684

Gene Accession:

BC011902

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.