中文名稱:CAPRIN1抗原(重組蛋白)
英文名稱: CAPRIN1 Antigen (Recombinant Protein)
別 名: M11S1; GPIAP1; RNG105; GPIP137; p137GPI
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human CAPRIN1 |
Full name: |
cell cycle associated protein 1 |
Synonyms: |
M11S1; GPIAP1; RNG105; GPIP137; p137GPI |
Swissprot: |
Q14444 |
Gene Accession: |
BC001731 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Caprin-1 is a protein that in humans is encoded by the CAPRIN1 gene. May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. May form homomultimers. Directly interacts with G3BP1 in cytoplasmic RNA granules. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs. |