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  • MCM2抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16822
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:40
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中文名稱: MCM2抗原(重組蛋白)

英文名稱: MCM2 Antigen (Recombinant Protein)

別       名: BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN

儲       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to C terminal 300 amino acids of human MCM2

技術(shù)規(guī)格

Full name:

minichromosome maintenance complex component 2

Synonyms:

BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN

Swissprot:

P49736

Gene Accession:

BC007670

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.