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  • GRAP抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16658
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:60
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中文名稱: GRAP抗原(重組蛋白)

文名稱: GRAP Antigen (Recombinant Protein)

儲(chǔ)     存: 冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

GRB2-related adaptor protein

Swissprot:

Q13588

Gene Accession:

BC035856

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.