兔抗CYB561D2多克隆抗體

Background:

CYB561D2 (Cytochrome b561 domain-containing protein 2), also known as putative tumor suppressor protein 101F6, is a 222 amino acid highly hydrophobic protein that contains six membrane spanning domains. Localized to endosomes and endoplasmic reticulum of the perinuclear region, CYB561D2 contains 2 heme-binding sites, through which it reduces ferric ions. CYB561D2 is ubiquitously expressed, with highest levels in lung, liver and kidney. Though expression of CYB561D2 is abundant in normal lung bronchial epithileal cells, CYB561D2 is absent in most lung cancers. The gene encoding CYB561D2 maps to human chromosome 3p21.3, a region that is prone to genetic alterations and is associated with frequent and early allele loss in many human cancers.

Applications:

WB

Name of antibody:

CYB561D2

Immunogen:

Synthesized peptide derived from internal of human C56D2.

Full name:

cytochrome b561 family, member D2

Synonyms：

101F6; TSP10; XXcos-LUCA11.4

SwissProt:

O14569

WB Predicted band size:

24 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000