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  • BIRC7抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16163
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：60
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中文名稱： BIRC7抗原（重組蛋白）

英文名稱： BIRC7 Antigen (Recombinant Protein)

別     名： KIAP, LIVIN, MLIAP, RNF50, ML-IAP

儲(chǔ)     存： 冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

baculoviral IAP repeat containing 7

Synonyms:

KIAP, LIVIN, MLIAP, RNF50, ML-IAP

Swissprot:

Q96CA5

Gene Accession:

BC014475

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.