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  • AKR1C4抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16140
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱： AKR1C4 抗原（重組蛋白）
英文名稱： AKR1C4 Antigen (Recombinant Protein)
別      名： aldo-keto reductase family 1, member C4; C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD
儲(chǔ)      存： 冷凍（-20℃）
相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 1-323 amino acids of human AKR1C4

技術(shù)規(guī)格

Full name:

aldo-keto reductase family 1, member C4

Synonyms:

C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD

Swissprot:

P17516

Gene Accession:

BC020744

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.