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  • ARC抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW15970
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱(chēng):ARC抗原(重組蛋白)

英文名稱(chēng):ARC Antigen (Recombinant Protein)

別      名: Arg3.1

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類(lèi)別抗原

概      述:

Fusion protein corresponding to a region derived from C terminal 298 amino acids of human ARC


技術(shù)規(guī)格:

Full name:

activity-regulated cytoskeleton-associated protein

Synonyms:

Arg3.1

Swissprot:

Q7LC44

Gene Accession:

BC012321

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.