Fusion protein corresponding to a region derived from 194-393 amino acids of human HENMT1 |
技術(shù)規(guī)格
Full name: |
HEN1 methyltransferase homolog 1 |
Synonyms: |
HEN1; C1orf59 |
Swissprot: |
Q5T8I9 |
Gene Accession: |
BC012198 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis. |