兔抗LIMK2(Ab-283) 多克隆抗體

Background:

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain.

Applications:

WB

Name of antibody:

LIMK2(Ab-283)

Immunogen:

Synthesized non-phosphopeptide derived from human LIMK2 around the phosphorylation site of serine 283 (R-R-S(p)-L-R).

Full name:

LIM domain kinase 2

Synonyms：

0

SwissProt:

P53671

WB Predicted band size:

72 kDa

WB Positive control:

NIH/3T3 cells treated with PMA (125ng/ml, 30mins) lysate

WB Recommended dilution:

500-3000