兔抗KLK4多克隆抗體

Background:

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined.

Applications:

ELISA, IHC

Name of antibody:

KLK4

Immunogen:

Fusion protein of human KLK4

Full name:

kallikrein-related peptidase 4

Synonyms：

ARM1; EMSP; PSTS; AI2A1; EMSP1; KLK-L1; PRSS17; kallikrein

SwissProt:

Q9Y5K2

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer and human thyroid cancer

IHC Recommend dilution:

25-100