Background: |
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. |
Applications: |
ELISA, IHC |
Name of antibody: |
KLK2 |
Immunogen: |
Synthetic peptide of human KLK2 |
Full name: |
kallikrein-related peptidase 2 |
Synonyms: |
hK2, hGK-1, KLK2A2 |
SwissProt: |
P20151 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human liver cancer and Human ovarian cancer |
IHC Recommend dilution: |
50-200 |