中文名稱:兔抗ABCB11多克隆抗體
英文名稱: Anti-ABCB11 rabbit polyclonal antibody
別 名: BSEP; PGY4; SPGP; ABC16; BRIC2; PFIC2; PFIC-2
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: ABCB11
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. |
Applications: |
ELISA, IHC |
Name of antibody: |
ABCB11 |
Immunogen: |
Synthetic peptide of human ABCB11 |
Full name: |
ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
Synonyms: |
BSEP; PGY4; SPGP; ABC16; BRIC2; PFIC2; PFIC-2 |
SwissProt: |
O95342 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human ovarian cancer and Human lung cancer |
IHC Recommend dilution: |
15-50 |